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Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy

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The absence of OCTN3 in humans, together with the OCT1 functional difference between humans and rodents, is a critical issue that limits the use of mice as a model

A range of 2,000 mg to 3,000 mg is generally recommended

Although its uncertain what caused these conflicting results, all these clinical trials suffered from flaws such as small sample sizes and short duration