Although the exact mechanism is unclear, this finding is consistent with the suggestion that thrombosis is also inflammatory-mediated
8 It seems, reviewing the published literature and the LOVD (www.lovd.nl), and HGMD (www.hgmd.cf.ac.uk) databases, that clEDS is often caused by gene conversion events and this is the most common recurrent mechanism of pathogenicity
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Female GLPDRKO mice experienced a significant increase in lean mass and maintained fat mass, leading to an overall neutral impact of cold stress on body weight gain, independent of housing temperature (Fig