Saxenda is a GLP-1 receptor agonist licensed for weight management in adults with BMI 30 kg/m or 27 kg/m with comorbidities Plateaus occur due to metabolic adaptation, reduced energy expenditure, dietary adherence decline, and hormonal changes during weight loss Treatment should be discontinued after 12 weeks on 3.0 mg if less than 5% initial body weight has been lost, per NICE guidance Accurate calorie tracking, increased protein intake, and progressive physical activity are evidence-based strategies to overcome plateaus Seek urgent medical attention for severe abdominal pain, gallbladder symptoms, or persistent vomiting which may indicate serious complications Table of Contents Understanding Weight Loss Plateaus on Saxenda Why Saxenda May Stop Working After Initial Success Evidence-Based Strategies to Restart Weight Loss on Saxenda When to Speak with Your GP About Your Saxenda Plateau Lifestyle Adjustments That Support Saxenda Effectiveness Scientific References Frequently Asked Questions Understanding Weight Loss Plateaus on Saxenda A weight loss plateau whilst taking Saxenda (liraglutide 3.0 mg) is a common and often frustrating experience

Sorescu D, Weiss D, Lassegue B, Clempus RE, Szocs K, Sorescu GP, Valppu L, Quinn MT, Lambeth JD, Vega JD, Taylor WR, Griendling KK
If you are over 55 and starting a GLP-1 drug, muscle preservation should be a primary goal of your treatment plan, not an afterthought
Powerful Detoxification 2
Most of these calls were due to severe side effects commonly associated with semaglutide, such as nausea, vomiting, and stomach pain, which were typically managed with intravenous fluids and anti-nausea medications