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The trial was stopped early for efficacy following a prespecified interim analysis triggered in October 2023 when two-thirds of the total planned number of primary outcome events had occurred
2019, DOI: 10.1021/acs.joc.9b03280)
Accordingly, the significance of UV photofunctionalization may not lie solely in enhancement of osseointegration itself, but rather in its potential to simultaneously influence three interrelated interface domains central to peri-implant health: microbial colonization, mucosal barrier formation, and biologic/mechanical implant stabilization
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