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The weight of these studies is between 10.1 and 23.4%, and the total number of participants is between 3297 and 9901

The use of statins at higher concentrations than in the present study has been previously associated with varying effects on insulin secretion: simvastatin was shown to reduce, while pravastatin increased insulin secretion in response to glucose, with GLP-1 or exendin-4 exposure restoring secretory responses from statin-treated cells (48)

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By mimicking glucagon-like peptide-1 (a natural hormone), these medications slow stomach emptying, increase satiety, and improve insulin secretion

However, some protocols may require multiple pens to complete a full course