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In the STEP clinical trials, participants taking semaglutide lost an average of 15-20% of their body weight over 68 weeks, compared to a 2.4% weight loss in those who received a placebo

Williams and Goldman-Rakic, 1995

The presence of senescence markers within lesions suggests that senescence is not merely a consequence of the patients overall chronological age but is likely induced locally within the disease environment [54]

Medication modification will likely be accompanied by a conversation about lifestyle factors, such as eating and exercise