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The Mayo Clinic shares that those most at risk of low levels include (5): people who dont consume enough vitamin B12 in their diet people diagnosed with pernicious anemia people whove had gastric surgeries people with intestinal issues, such as celiac or Crohns disease People following a vegetarian diet are especially at risk of deficiency

Multivitamin products typically contain lower doses (around the daily intake target), while single-nutrient vitamin B12 dietary supplements can range from 50 to 1,000 mcg

Deficiency of folate with or without vitamin B12 deficiency impairs DNA synthesis, leading to cell death, ineffective red blood cell production, and anemia