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chronic liver disease and hepatitis may present with elevated levels Renal impairment : Reduced clearance can contribute to accumulation, though this is rarely clinically significant Solid tumours : Certain malignancies, particularly hepatocellular carcinoma and metastatic disease, may elevate B12 levels [3] Evidence suggests that unexplained markedly elevated B12 levels without supplementation may sometimes be associated with underlying disease

Thus, vitamin B12 is especially awarded a function in the DNA synthesis of myelinproducing oligodendrocytes and the synthesis of myelin

10.1016/j.clinthera.2011.03.003 [DOI] [PubMed] 29.Kuzminski AM, del Giacco EJ, Allen RH et al (1998) Effective treatment of cobalamin deficiency with oral cobalamin

That coordination bond is pH-sensitive, temperature-sensitive, and oxygen-sensitive

If they do not fit, I will say so