In recent years, it has been found that incretin, the star drug of hypoglycemic and weight loss, is also involved in bone remodeling regulation, in which GIP can inhibit postprandial bone absorption, and GLP-1 also indirectly mediates acute and short-term inhibition of bone resorption through hyperphysiological concentrations of insulin [54]
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For simplicitys sake, well call the forms R and S. The R form is biologically active in your body
Cemeroglu AP, Kocaba CN, Cokun T, Grgey A (2001)
What does nerve growth factor do for the brain