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Fatigue Cold hands and feet Sleep disturbances or vivid dreams Bradycardia (slow heart rate) Propranolol should be used cautiously in patients with asthma or certain heart conduction problems

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Statistical methods Participants demographic data were summarized with descriptive statistics (mean and standard deviation for continuous variables, number and percent for categorical variables)

When GSSG/GSH was excessive in the reaction system and GR activity became the rate-limiting step, the formation rate of TNB is positively correlated with GR activity

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