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Principal component analysis (PCA) revealed clear separation among the three groups at the transcript level, suggesting that RT induces reproducible gene expression changes, with EGCG-Zn treatment more closely resembling those of normal mice, suggesting that it modulates these changes to some extent (Fig

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In 2023 the American Academy of Pediatrics (AAP) and other expert bodies began endorsing earlier consideration of pharmacotherapy: weight-loss medications are now recommended for youth aged 12 (and even younger in controlled settings) who have obesity or overweight with comorbidities, after insufficient response to intensive lifestyle therapy

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10.1007/s12011-020-02515-y 71 WangX.HanY.ChenF.WangM.XiaoY.WangH.et al (2022)