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Increased serum advanced glycation end products is a distinct finding in lean women with polycystic ovary syndrome (PCOS)
Key areas analyzed included the prelimbic cortex, anterior olfactory nucleus, nucleus accumbens, lateral septal nucleus, bed nucleus of stria terminalis, ventral reuniens, paraventricular and ventromedial hypothalamic nuclei, hippocampal CA1 and CA2/3 regions, and the central amygdaloid nucleus
PIONEER 4: Head-to-head vs liraglutide 1.8 mg 11 Study design: 52-week, randomized, double-blind, double-dummy, active controlled, and placebo-controlled phase 3a trial designed to assess the safety and efficacy of semaglutide tablets vs subcutaneously injected GLP-1 RA, liraglutide
doi: 10.4149/endo_2012_01_3 125 PeverelliEGiardinoEMangiliFTreppiediDCatalanoRFerranteEet al