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Proposed mechanisms The following section describes mechanistic hypotheses proposed in the included studies and broader literature

GIP receptor activation adds further effects on fat metabolism and glucose handling

Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia

Ozempic causes diarrhea through multiple mechanisms: it slows gastric emptying while potentially accelerating intestinal transit, alters gut motility, changes how the intestines absorb nutrients like sugar and fats which can irritate the intestines, and can alter the gut microbiome composition

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