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The management of patients with DSPN involves the control of individualized cardiometabolic targets, a multidisciplinary approach aimed at the prevention and management of foot complications, and the timely diagnosis and management of neuropathic pain

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In contrast, its endogenous production is generated either from glucose by enzymatic reactions or by de novo catabolism of phosphatidylinositol (PI), phosphoinositides (PIP), and inositol phosphates (IP)

The decline in cellular energy during the human aging process is one of the factors that accelerates aging

Secreted by enteroendocrine L cells in response to nutrient intake, GLP-1 enhances glucose-dependent insulin secretion, suppresses glucagon release, delays gastric emptying, and promotes satiety