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Although the animal model used in this study reduced the risk of acute rejection, it failed to fully simulate the long-term immunosuppressive state of clinical transplant recipients, which may lead to bias in the evaluation of the fibrosis process of human kidney transplantation

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It has shown significant promise as an effective intervention against type 2 diabetes (T2D) and excessive body weight, resulting in the United States Food and Drug Administration (FDA) approving its use against both conditions in May 2022 for T2D and November 2023 for obesity