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Statistics Statistics were run using GraphPad Prism (v7.05) unless specified otherwise

The structural models were built using Coot (Emsley et al., 2010) and crystallographic refinement was performed with Phenix.refine (Afonine et al., 2012) including the addition of hydrogens in riding positions and TLS-refinement

A branched small amino acid in position 15 (Thr or Val) is probably necessary to restrict the binding mode of SA (Fig

10.1042/BJ20040004 161 LiuH.ForouharF.SeibtT.SanetoR.WigbyK.FriedmanJ.et al (2022)

No existe evidencia concluyente de que ningn suplemento pueda replicar los efectos de los cambios dietticos y de estilo de vida, o de los medicamentos basados en GLP-1 cuando estn mdicamente indicados