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Assistance programs, insurance coverage reviews or generic alternatives (if available) may be safer ways to address cost issues. Before theyre able to be marketed, FDA-approved medications like Ozempic, Wegovy and Rybelsus are required to go through clinical trials to show theyre safe and effective for their intended purpose

Plant polyphenols, for example, are well-established hormetins 25,26

While it showed promise in preclinical studies and limited human trials, it was never advanced to late-stage clinical development or FDA approval

At the 2024 Alzheimer's Association International Conference, early results showed that people in early stages of Alzheimer's who took the GLP-1 drug liraglutide daily for a year lost almost 50 percent less brain volume in key areas tied to memory and thinking