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In men, nitric oxide may play a role in erectile function, as it may promote relaxation of penile arteries, allowing for increased blood flow to help achieve and maintain an erection[2]

In a study involving rats, prednisolone, a glucocorticoid, was found to increase the hepatic capacity for urea-N synthesis (CUNS) and elevate the expression of urea cycle genes, which contributes to nitrogen loss

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