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Myometry data from children five years of age and older indicated that upper extremity strength was greater in the placebo group (Supplemental Table S5, p.03), but lower extremity myometry data demonstrated no difference between groups

Outcome events of interest include time to: histological progression to cirrhosis, uncontrolled ascites, HCC, liver transplantation/transplant eligibility, and hospitalisation for hepatic decompensation or death.85 Key Point Currently OCA is being evaluated in a large phase III, randomised, placebo-controlled trial Elafibranor Elafibranor is another agent currently in phase III for the treatment of NASH

Each puncture is an opportunity for microbial entry

111 , QT (1050 M) was adequate to increase CYP11A1 promoter activity