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Taken together, these observations support a model in which BL mitigates PD-associated neurodegeneration through multimodal anti-inflammatory mechanisms, including inhibition of NF-B nuclear translocation, downregulation of p65 signaling, suppression of NLRP3 inflammasome assembly, and reduction of pro-inflammatory cytokine production
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NLRP3 inflammasome-driven pathways in depression: clinical and preclinical findings
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