Well-structured treatments lasting 6-12 months with appropriate concentrations typically maintain noticeable improvements over pre-treatment baseline including reduced fine lines (though not eliminated as during peak treatment), improved skin texture and firmness (though less dramatic than treatment peak), better overall skin quality and appearance (though aging continues at normal rates), and resolved specific issues like scarring or hyperpigmentation (which typically remain improved permanently if successfully treated)
Packaging can differ from U.S
17.Standing Committee on the Scientific Evaluation of Dietary Reference Intakes Panel on Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids and the Subcommittee on Upper Reference Levels of Nutrients, Food and Nutrition Board, Institute of Medicine (IOM)
When it functions at its best, it lets any charged ions begin flowing thru the cell membrane
The most important factor is consistency of timing and route day to day, since the mechanism works cumulatively rather than as an acute event to time around a meal