The subcutaneous conversion, combination pipeline, and new indication filings are Mercks primary defenses
Moreover, GLP-1 does not affect energy expenditure in humans [28] which means that this treatment does not compensate for the reduction in energy expenditure that is observed with weight loss, a phenomenon that again limits the weight loss associated with GLP-1 analogue treatment
Alternative reconstitution, with stronger concentration Add 1ml of bacteriostatic water to 5mg vial This creates: 5,000mcg per ml (5mcg per unit on insulin syringe) Smaller injection volume : 250mcg dose = 0.05ml = 5 units 500mcg dose = 0.10ml = 10 units Preferred if you want minimal injection volume
But Eli Lilly CEO David Ricks said on the call that the company is "aggressively planning" further production buildup for Mounjaro and other drugs
February 2025 A study published January 30, 2025, found that medications like Ozempic, commonly used to treat diabetes and aid in weight loss, may be linked to rare eye conditions that can cause vision loss or even blindness
