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For most people they ease off after a few weeks, but during that initial period they can be uncomfortable enough to interfere with daily routine

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Common adverse events included gastrointestinal discomfort (9 RCTs, 24 subjects), dizzy (11 RCTs, 22 subjects), nausea (12 RCTs, 18 subjects), hypoglycemia (10 RCTs, 17 subjects), diarrhea (9 RCTs, 14 subjects), vomit (9 RCTs, 13 subjects), loss of appetite (5 RCTs, 10 subjects), rash (5 RCTs, 9 subjects) (Supplementary Table S16)