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Description

Deficiency compromises intrinsic defensive capacity, whereas overload directly instigates oxidative and proteotoxic stress, including crosstalk with ferroptosis [166]

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Combination therapy has also demonstrated efficacy: the combination of NR with L-carnitine enhanced fatty acid transfer and NAD + elevation, yielding superior hepatoprotection in comparison with NR alone (Salic et al

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doi: 10.1038/s41418-018-0102-y 57 StraussJFiggWD

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Moreover, we also found that a strict relationship exists between the level of the GSH intracellular content, anti-apoptotic protein Bcl-2 and the intensity of influenza virus replication

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