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these changes were similar to those observed in NP-S rats

Heffernan MA, Thorburn AW, Fam B, et al

SIRT3 lysine deacetylase inhibitors specifically target SIRT3 without affecting its structurally similar counterparts, SIRT1 and SIRT2 185,186

It also neutralizes free radicals

*Correspondence: Xiaoming Zhou, [email protected] This article was submitted to Molecular Diagnostics and Therapeutics, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers