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Reduced glutathione (GSH) is the active, stable form of the antioxidant

10.1016/j.cell.2013.01.013 146 MuthukumaranK.KanwarA.VeghC.MargineanA.ElliottA.GuilbeaultN.et al

On the other hand, in case of excessive distress, cells are exposed to high levels of ROS which can cause neuroinflammation, damage to the blood-brain barrier (BBB) and impairment to astrocyte crosstalk leading to ASD (Russo et al., 2018)

This hypermetabolic state results in enhanced glycolysis and increased ROS production, exacerbating oxidative stress

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