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4.3 Neuroinflammation and immune signaling interference Beyond supporting energy metabolism, FAD and FMN critically modulate neuroinflammatory pathways by influencing signaling cascades such as TNFR1/NF-B, MAPK, and PI3K-Akt

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The intestinal epithelium-specific Satb2 knockout mice (Satb2 f/f ;Vil Cre ) used in this study have been previously described in our research [4]