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Grip-intensive movements and repetitive elbow flexion and extension under load are the primary drivers

As expected, the K D values of these peptides were nearly identical to those of their parent peptides in Met ectodomain SPR measurements, whereas a control peptide derived from the scrambled aMD4 sequence (aMsD4-Fluo) showed no detectable binding

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Here, nontryptic peptidomic mass spectrometry was performed on 102 post-mortem cortical samples from individuals across cognitive and neuropathological spectra