Therefore, for drugs like doxorubicin or cisplatin to achieve therapeutic efficacy, they must first be released from the liposomal carrier into the tumor microenvironment and subsequently diffuse across the cellular membrane into the intracellular space [103]
However, GDH activity in the rat liver does not vary with age (Prabhakaram and Singh, 1988)
A better understanding of the changes of oxidative stress and sleep is crucial for developing methods that directly enhance sleep dependent plasticity, since promoting sleep may be useful to restore synaptic plasticity in different pathological conditions

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