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While the clinical impact varies, it is important to consider timing and dosing adjustments

Funding This work was partially supported by the Puerto Rico Science, Technology and Research Trust award, and the following grants from the National Institutes of Health: NIGMS/MBRS Grant GM08224, NIMHD RCMI-Infectious and Global Diseases Center Grant G12MD007600, and NIMHD CCRHD-Tropical Emerging Infectious Diseases Research Center Grant U54MD007600