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How MSCs May Influence Autism Biology In preclinical models, MSC therapy has been associated with: Reduced neuroinflammation Decreased microglial activation Increased production of neurotrophic factors Enhanced synaptic plasticity Improved neuronal survival In mouse models of autism, MSC treatment has been linked to improvements in social interaction and reductions in repetitive behaviors

It is not surprising that both sulfation- and glutathione-dependent pathways are aberrant in the same population because they are metabolically connected [41,72,73]

In patients who are near their glycemic goal when treatment is initiated the recommended starting dose of nateglinide is 60 mg three times per day before meals

228 From a psychological standpoint, hearing loss is associated with depression, anxiety, and social isolation