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J Biol Chem (2015) 290:2178899.10.1074/jbc.M115.654582 13 KobayashiMLiLIwamotoNNakajima-TakagiYKanekoHNakayamaYet alThe antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds