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Some of the oncogenes increasing the IGF-1R promoter activity can also affect IGF-1R action by nontranscriptional mechanisms

The pulse it produces is sharp but brief, which is the single biggest practical limitation compared to modern alternatives

Quercetin enhances chemotherapeutic effect of doxorubicin against human breast cancer cells while reducing toxic side effects of it

In addition to definitions, new biomarkers and tests for diagnosing immune-related side effects are needed, and that will require collaboration from experts across disciplines, he said

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