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GPS has been observed to suppress the expression or activity of certain CDKs and cyclins essential for the transition from the G0/G1 phase to the S phase ( In the context of cellular migration, GPS has been shown to suppress the activity of matrix metalloproteinases (MMPs), a group of enzymes crucial for the breakdown of the extracellular matrix (ECM)

PDHA1 knockdown significantly suppressed tumor growth and enhanced the therapeutic effects of Enz, as evidenced by decreased tumor volume and weight (Fig

But these side effects are very rare

155 Additionally, the lactylation of K388 on NBS1, another crucial HR protein, promotes DNA repair by affecting the formation of MRN complexes

Maternal N-acetyl-cysteine (NAC) protects the rat fetal brain from inflammatory cytokine responses to lipopolysaccharide (LPS)