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Its mechanism is purely metabolic: it directly targets lipid metabolism via inhibition of NNMT and restoration of cellular NAD+
Retatrutide is different from other GLP-1 receptor agonists because it targets three receptors: GLP-1, GIP, and glucagon
As their popularity soars, rare and serious side effects are emerging
In patients with Addisonian Pernicious Anemia, parenteral therapy with vitamin B12 is the recommended method of treatment and will be required for the remainder of the patients life
Mounjaro is being rolled out through GP surgeries in stages, currently for people with a BMI of 35 or above plus at least four weight-related conditions, and Wegovy is available through specialist services
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