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215 Cyst(e)inase degrades extracellular cysteine and cystine and leads to decreased levels of intracellular cysteine and glutathione, which profoundly affects the redox potential of cancer cells 216 and counteracts the essential role of cysteine in cancer cells

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The standard dosing protocol starts at 15mg daily and can increase to a maximum of 37.5mg once per day, usually taken in the morning to avoid insomnia