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Beyond passive data analysis, future AI tools will be embedded into closed-loop systems capable of real-time interpretation and actuation, adjusting drug release or material properties based on dynamic physiological feedback

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Notwithstanding the strides achieved in genetic manipulation and regenerative technologies, L-DOPA or compounds related to dopamine metabolism such as MAO-B inhibitors remain as the major modes of palliative care for PD patients 39,56

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