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Hyperbaric oxygen preconditioning protects cortical neurons against oxygen-glucose deprivation injury: role of peroxisome proliferator-activated receptor-gamma

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Reduced electrophilicity, however, does not necessarily translate into proportionally reduced chemoproteomic labelling, as local cysteine microenvironments and experimental conditions can substantially modulate apparent proteome-wide engagement, thereby explaining the observed differences in labelling promiscuity across the chemoproteomic probes in the set