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Copper is required for cytochrome c oxidase, one of the key enzymes involved in mitochondrial energy production

While the same cant be said for every joint in the body, its well known that weight loss still helps relieve pressure, and other studies have shown that people who are able to lose 20% of their starting weight experienced roughly 25% less pain, improved knee function, and improved quality of life compared to those who only lost 5 to 10% of their original body weight

Lancet 397 , 22122224 (2021)

Qiu L, Shen R, Wei L, Xu S, Xia W, Hou Y, et al

Improved Insulin Sensitivity: In addition to its weight loss benefits, Semaglutide has demonstrated positive effects on insulin sensitivity