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Lower contents were observed in callus treated with 8 mg L -1 SiO 2 NPs (20.880.19 g g -1 FW) and 2 mg L -1 ZnONPs (20.010.03 g g -1 FW), while their respective bulk materials showed even lower values (Fig

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However, in Idiopathic Pulmonary Fibrosis (IPF), a chronic lung disease that shares some pathological features with CF, including fibrosis and significant oxidative stress, plasma proteomics has identified haptoglobin-related protein as a potential biomarker, being involved in antioxidant responses, alongside evidence of dysregulated oxidative pathways (Saraswat et al., 2020)