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For others, it might take a little longer

When to contact your healthcare provider Contact your healthcare provider right away if you have: severe or persistent side effects vomiting that does not stop severe stomach pain trouble breathing swelling of the face or throat signs of dehydration yellowing of the skin or eyes confusion or fainting vision changes References Anthony, M

Watch for increasing fatigue, cold intolerance, constipation beyond what tirzepatide typically causes, dry skin, hair thinning, depression, or unexplained weight gain despite following your diet protocol

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