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However, some individuals may experience: Injection site reactions such as mild redness, itching, or swelling Water retention or mild fluid buildup, particularly in the early weeks Joint discomfort or stiffness, which often resolves as the body adjusts Tingling or numbness in the hands or feet (less common) Elevated blood glucose levels in individuals predisposed to insulin resistance It is worth noting that tesamorelin should not be used by individuals with active cancer, those who are pregnant, or patients with hypersensitivity to its components

Take part in some physical activity, even if it's only walking

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In real-world practice, those discontinuation rates may be even higher. Andrade said the medication could be helpful for people with severe obesity, who may still have trouble losing weight on the existing GLP-1 medications, although shed like to see more data on the side effects