What do we know about this specific medication during breastfeeding
Beaulieu, J
Harmful alcohol consumption is estimated to contribute to over 5% of global deaths and is the leading cause of preventable mortality.74 Additionally, approximately 5 million people worldwide are estimated to have cocaine use disorder145 and approximately 58 million individuals use opioids, including synthetic variants.146 The pathophysiology of addiction has been extensively investigated, revealing drug-induced dysregulation of multiple neural circuits and neurochemical systems, including dopamine, opioid peptides, corticotropin-releasing factor, dynorphin, glutamate, and gamma-aminobutyric acid (GABA)
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Although an inflammatory phenotype was not detected in the brain, systemic immune dysregulation was suggested by significant decreases of IFN, TNF, IL-1, and IL10 (Zakirova et al., 2017)
