glp-1 mechanism of action diabetes Recent updates on agonists: Current advancements & challenges The protective role of GLP-1

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A single intranasal application of Semax at 50 mcg/kg body weight produces a 1.4-fold increase in BDNF protein levels in the rat hippocampus, accompanied by a 1.6-fold increase in TrkB tyrosine phosphorylation and a 3-fold increase in exon III BDNF mRNA levels

Figure 2 presents a schematic flowchart illustrating the sequential steps involved in the mechanism of GLP-1 action