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J Am Acad Dermatol 55:10141023

READ MORE- Early diabetes symptoms: The 10 warning signs of diabetes Vitamin B12 deficiency symptoms A deficiency in Vitamin B12 or folate can cause a wide range of unpleasant symptoms, including: Extreme tiredness A lack of energy Pins and needles (paraesthesia) A sore and red tongue Mouth ulcers Muscle weakness Disturbed vision Psychological problems, which may include depression and confusion Problems with memory, understanding and judgement If youre experiencing any of the above, see your GP to get a diagnosis and treatment

While chaA encodes a characterized Na + (Ca 2+ )/H + antiporter, chaB and chaC were originally identified as putative, though uncharacterized, regulators of chaA (Oshima et al., 1996)