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Because the normal daily requirement for B12 is only about 2.4 mcg, this passive absorption is more than enough to keep your levels healthy and correct the deficiency [9] [10]

Individual variability in glycine metabolism, baseline dietary intake, and genetic factors likely influence response

Cofactor for L-methylmalonyl-coenzyme A mutase 5-Deoxyadenosylcobalamin is required by the enzyme that catalyzes the conversion of L-methylmalonyl-coenzyme A to succinyl-coenzyme A (succinyl-CoA), which then enters the citric acid cycle ( Figure 2 )

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This is one reason why alcoholism causes B12 deficiency