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Contraindications Vitamin B12 injection is contraindicated in pregnant and lactating women, liver disease, kidney disease, infection, iron deficiency, folic acid deficiency, the patient undergoing treatment that has a direct effect on bone marrow, an allergy to medication, vitamin, preservative or cobalt

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User 3 split his 500mcg dose as 250mcg every 12 hours specifically to account for what he cited as a 4 to 6-hour half-life

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