273 In malignant gliomas, BCAT c gene expression has been reported to be positively correlated with M2-type macrophages and Treg markers, 274 and GBM cells with high BCAT c expression can excrete BCKAs through monocarboxylate transporter 1 (MCT1)
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Coutinho F, Simes R, Oliva-Teles A, Oliva-Teles A, Peres H, Monge-Ortiz R, Furuya WM, Pouso-Ferreira P, Kaushik S (2017) Effects of dietary methionine and taurine supplementation to low-fish meal diets on growth performance and oxidative status of European sea bass (Dicentrarchus labrax) juveniles
The foundational mechanism underpinning these effects is the production of neuroactive metabolites by gut bacteria, which bear structural and functional resemblance to host-derived neurochemicals (448)
34 DervieuxT.MeyerG.BarhamR.MatsutaniM.BarryM.BoulieuR.et al (2005)