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Bacteria causing important diseases of citrus utilise distinct modes of pathogenesis to attack a common host

Senescent cells, despite their pro-inflammatory SASP, also suppress tumor progression in some contexts through 'senescence surveillance'nearby immune cells recognize and destroy newly senescent cells, including pre-malignant cells undergoing oncogene-induced senescence

GHK-CU demonstrates anti-inflammatory properties, helping reduce chronic inflammationa key driver of aging and age-related diseaseswhile supporting immune balance

doi:10.1152/ajplegacy.1959.197.1.217 43

For comparison, we treated cells with tunicamycin (TUN, a widely-used ER stress inducer) which did not alter phospho-GCN2 (T899), but reduced the mobility of PERK, indicative of its increased phosphorylation (Fig