Oligomycin, carbonyl cyanide m-chlorophenyl hydrazone (CCCP), and rotenone were obtained from Merck Millipore (Darmstadt, Germany)
Rather than mimicking a satiety hormone, it works upstream in the central nervous system: it triggers the release of norepinephrine, dopamine, and serotonin , which suppresses appetite and modestly increases energy expenditure
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As long-chain ACs are excreted and metabolized in the kidney, it might be the reason for the increase of serum AC levels in male uremic HD patients
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